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Team:IIT Madras/Dry lab/Modelling/Simulations
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| - | <p align="center"><b><u> Figure 1 and 2 : % Increase in growth rate observed due to Proteorhodopsin (Proton efflux = 2 and 10 mmol/g-dw hr) for varying glucose uptake rates respectively.</u></b></p><br/> | + | <p align="center"><b><u> Figure 1 and 2 : % Increase in growth rate observed due to Proteorhodopsin (Proton efflux = 2 and 10 mmol/g-dw hr) for varying glucose uptake rates respectively.</u></b></p><br/><br/> |
| + | <p> <b><u>According to the model the following reactions showed major flux changes due to Proteorhodopsin :</u></b> | ||
| + | <ol><li>'adentylate kinase GTP ' </li> | ||
| + | <li>'adenosine hydrolase' </li> | ||
| + | <li>'dihydroorotic acid menaquinone 8 </li> | ||
| + | <li>'3 isopropylmalate dehydrogenase' </li> | ||
| + | <li>'psicoselysine transport via proton symport periplasm </li> | ||
| + | <li>'purine nucleoside phosphorylase Deoxyadenosine ' </li> | ||
| + | <li>'L threonine via sodium symport periplasm ' </li></ol> | ||
| + | <u>Reaction Knockout Analysis of '3 isopropylmalate dehydrogenase' was lethal and the other reactions didn’t have major effects on growth rates .</u></p><br/> | ||
| + | <br/> | ||
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Revision as of 03:03, 29 October 2011
Simulations for Proof of Concept
Figure 1 and 2 : % Increase in growth rate observed due to Proteorhodopsin (Proton efflux = 2 and 10 mmol/g-dw hr) for varying glucose uptake rates respectively.
According to the model the following reactions showed major flux changes due to Proteorhodopsin :
- 'adentylate kinase GTP '
- 'adenosine hydrolase'
- 'dihydroorotic acid menaquinone 8
- '3 isopropylmalate dehydrogenase'
- 'psicoselysine transport via proton symport periplasm
- 'purine nucleoside phosphorylase Deoxyadenosine '
- 'L threonine via sodium symport periplasm '
