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From 2011.igem.org

The Lab

The Nuclear Receptor Research lab, led by Laszlo Nagy, focuses on the molecular and cell biology of lipid activated transcription factors, so called nuclear receptors. We are interested in the molecular details of hormone action. Lipid soluble hormones such as oestrogens and retinoids act via these receptors that bind to and regulate the expression of certain genes. The aim of the eleven PhD students, four postdocs and senior researchers, associated with several undergraduate students is to understand the details and molecular determinants of these interactions using molecular and cell biological approaches.

To do so, we target our questions from different aspects, applying high variety of techniques, including basic RNA and protein biology, advanced microscopy, animal models, microarray techniques and bioinformatics. The Genomics Center is a core facility and research laboratory, a unit of the Department of Biochemistry and Molecular Biology (University of Debrecen Medical and Health Science Center). It has been established to support the University of Debrecen scientific community, as well as other academic research teams interested in using high-throughput genomics and bioinformatics for their research projects. We put special emphasis on supporting clinical genomics projects investigating the pathomechanism of diseases or searching for novel drug targets.