Team:UC Davis/Project
From 2011.igem.org
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<h1>Overview</h1> | <h1>Overview</h1> | ||
This year, we're focusing on the LacI, TetR, and cI Lambda repressors and their respective promoters. Our goal is to obtain a variety of behaviors from each of these parts by changing their sequences randomly, or mutating them. With this range of behaviors, we'll be able to design systems to exhibit targeted behavior depending on the chosen repressor. This will be a valuable contribution to the registry which contains many parts that have a limited range of activities such as always strongly on or inducible. Having a well-characterized range of activity of a single part will provide more opportunities to fine tune a system with an added layer or regulation. When coupled with another part that has a similar range of activity, a repressible promoter with a repressor for example, there is a combinatorial effect which gives the user even more control. | This year, we're focusing on the LacI, TetR, and cI Lambda repressors and their respective promoters. Our goal is to obtain a variety of behaviors from each of these parts by changing their sequences randomly, or mutating them. With this range of behaviors, we'll be able to design systems to exhibit targeted behavior depending on the chosen repressor. This will be a valuable contribution to the registry which contains many parts that have a limited range of activities such as always strongly on or inducible. Having a well-characterized range of activity of a single part will provide more opportunities to fine tune a system with an added layer or regulation. When coupled with another part that has a similar range of activity, a repressible promoter with a repressor for example, there is a combinatorial effect which gives the user even more control. | ||
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+ | <h2>General Construct</h2> | ||
+ | <img src="https://static.igem.org/mediawiki/2011/2/21/UCD_Gen_pMut_construct.png"> | ||
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</div> | </div> | ||
Revision as of 23:29, 19 September 2011
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