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Team:Peking S
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Revision as of 04:32, 14 July 2011
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PROJECT SUMMARY
There are many hindrances in construction of complex gene circuits, such as crosstalk between cellular elements, noise cascade as the increase of network complexity, and metabolic burden. Distributing complex gene circuits into different cells is one of valid methods to solve those problem. Among those, the most significant problem is the shortage of cell-cell communication systems. In order to solve that, we characterize two kind of cell-cell communication molecules .One of them is (S)-3-hydroxytridecan-4-one which is synthesized by Vibrio cholerae, and another is 2-isocapryloyl-3R-hydroxymethyl-g-butyrolactone synthesized by Streptomyces griseus . And AND , NOR , XOR gates will be constructed to prove their capabilities in building cell-cell communication system. As a result, we achieve to use one kind of cell to control the ratio of two kind of cells living together.
