Team:UT Dallas/Project

From 2011.igem.org

(Difference between revisions)
 
(37 intermediate revisions not shown)
Line 397: Line 397:
<div class="main">
<div class="main">
   <div class="header">
   <div class="header">
-
     <div class="logo">
+
     <div class = "logo">
-
       <h1><a href="index.html"><span>UTDallas </span> iGem 2011<small></small></a></h1>
+
   
 +
       <h1><span>UTDallas</span> iGem<small></small></h1>
     </div>
     </div>
-
<br></br>
+
 
     <div class="menu_nav">
     <div class="menu_nav">
-
<br></br>
+
 
       <ul>
       <ul>
-
         <li><a href="https://2011.igem.org/Team:UT_Dallas"><font size="3" face="helvetica">Home</a></font></li>
+
         <li><a href="https://2011.igem.org/Team:UT_Dallas"><font size="3" face="verdana">Home</a></font></li>
-
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Project"><font size="3" face="verdana">Team</a></font></li>
+
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Team"><font size="3" face="verdana">Team</a></font></li>
-
         <li class = "active"><a href="https://2011.igem.org/Team:UT_Dallas/Project2"><font size="3" face="verdana">Project</a></font></li>
+
         <li class = "active"><a href="#"><font size="3" face="verdana">Project</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Protocols"><font size="3" face="verdana">Protocols</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Protocols"><font size="3" face="verdana">Protocols</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Parts"><font size="3" face="verdana">Parts</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Parts"><font size="3" face="verdana">Parts</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Modeling"><font size="3" face="verdana">Modeling</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Modeling"><font size="3" face="verdana">Modeling</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Notebook"><font size="3" face="verdana">Notebook</a></font></li>
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Notebook"><font size="3" face="verdana">Notebook</a></font></li>
-
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Human Practices"><font size="3" face="verdana">Human Practices</a></font></li>
+
         <li><a href="https://2011.igem.org/Team:UT_Dallas/HumanPractices"><font size="3" face="verdana">Human Practices</a></font></li>
-
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Gallery"><font size="3" face="verdana">Gallery</a></font></li>
+
         <li><a href="https://2011.igem.org/Team:UT_Dallas/Safety"><font size="3" face="verdana">Safety</a></font></li>
          
          
       </ul>
       </ul>
Line 418: Line 419:
     </div>
     </div>
     <div class="clr"></div>
     <div class="clr"></div>
-
     <div class="hbg"><img src="https://static.igem.org/mediawiki/2011/b/b2/Original_Banner_for_UTD_website.png" width="968" height="300" alt="" />
+
     <div class="hbg"><img src="https://static.igem.org/mediawiki/2011/b/b2/Original_Banner_for_UTD_website.png" width="970" height="300" alt="" />
     <!-- <div class="text">
     <!-- <div class="text">
         <h3>Creating Futures</h3>
         <h3>Creating Futures</h3>
Line 429: Line 430:
       <div class="mainbar">
       <div class="mainbar">
         <div class="article">
         <div class="article">
-
   
+
          <h2><span>Overview</span></h2>
 +
          <p> <font size="3" face="verdana">The human bowel hosts a rich diversity of symbiotic microflora that provides a powerful engineering platform for intelligent probiotics. These “immunobots” will ideally work in-sync and enhance natural self-repair mechanisms for a range of intestinal diseases associated with tissue damage. Towards this end, we engineered a bacterial chemotaxis pathway that utilizes a chimeric receptor to successfully interface with the immune system. In addition, we introduced an inducible secondary bacterial population that can trigger system-wide self-destruction, conferring an additional level of user control. Each module of our system was characterized using fluorescent reporters and the integrated parts were evaluated by controlled experiments involving wound signal gradients. We envision a probiotic solution that can facilitate localized tissue repair for damage resulting from inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease.
 +
 
 +
</font></p><br></br>
 +
 
 +
 
 +
<br></br><br></br><br></br><br></br><br></br>
 +
          <div class="clr"></div>
 +
 
 +
          <!--<img src="images/images_1.jpg" width="613" height="193" alt="" /><br></br> Add pictures, diagrams, and captions here.<br></br>
 +
          <img src="images/images_1.jpg" width="613" height="193" alt="" /><br></br> Add pictures, diagrams, and captions here.<br></br>-->
-
         
+
                  <div class="clr"></div>
         </div>
         </div>
         <div class="article">
         <div class="article">
-
            <h2><span></span>UTD iGem 2011 Project Description</h2>
+
              </div>
-
<font size="3" face="verdana">Tissue damage characterizes a range of medical conditions that can be particularly difficult to manage without restrictively risky or expensive intervention. The human body hosts a rich diversity of symbiotic microflora that provides a powerful engineering platform for synthetic bacterial systems. We aim to construct a probiotic solution that successfully interfaces with the immune system to facilitate localized tissue repair.</font>
+
-
          <div class="clr"></div>
+
-
             
 
-
        </div>
 
         <!--<div class="pagenavi"><span class="pages">Page 1 of 2</span><span class="current">1</span><a href="#">2</a><a href="#" >&raquo;</a></div>-->
         <!--<div class="pagenavi"><span class="pages">Page 1 of 2</span><span class="current">1</span><a href="#">2</a><a href="#" >&raquo;</a></div>-->
       </div>
       </div>
       <div class="sidebar">
       <div class="sidebar">
-
      <!-- <div class="gadget">
+
        <div class="gadget">
           <div class="search">
           <div class="search">
-
            <form method="get" id="search" action="#">
+
         
-
               <span>
+
                
-
               <input type="text" value="Search..." name="s" id="s" />
+
                
-
              <input name="searchsubmit" type="image" src="https://static.igem.org/mediawiki/2011/e/e1/Search.gif
+
-
" value="Go" id="searchsubmit" class="btn"  />
+
-
              </span>
+
             </form>
             </form>
-
            <div class="clr"></div>
+
   
           </div>
           </div>
-
          <div class="clr"></div>
+
     
         </div>
         </div>
         <div class="gadget">
         <div class="gadget">
-
<div class="gadget">
 
-
<br></br>
 
-
-->
 
-
<br>
 
-
          <h2><span></span><font size="5" face="Arial">Explore Our Wiki!</font></h2>
 
-
          <div class="clr"></div>
 
-
          <ul class="sb_menu">
 
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas"><font size="3" face="verdana">Home</a></font></li>
 
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Project"><font size="3" face="verdana">Team</a></font></li>
 
-
            <li class = "active"><a href="https://2011.igem.org/Team:UT_Dallas/Project2"><font size="4" face="verdana">Project</a></font></li>
 
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Protocols"><font size="3" face="verdana">Protocols</a></font></li>
+
          <h2><span></span><font size="5" face="Arial">Subprojects</font></h2>
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Parts"><font size="3" face="verdana">Parts</a></font></li>
+
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Modeling"><font size="3" face="verdana">Modeling</a></font></li>
+
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Notebook"><font size="3" face="verdana">Notebook</a></font></li>
+
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/HumanPractices"><font size="3" face="verdana">Human Practices</a></font></li>
+
            <a href="https://2011.igem.org/wiki/index.php?title=Team:UT_Dallas/ProjectReceptor"><img src="
-
             <li><a href="https://2011.igem.org/Team:UT_Dallas/Gallery"><font size="3" face="verdana">Gallery</a></font></li>
+
https://static.igem.org/mediawiki/2011/8/86/Receptor.png" width="210" height="43"><br></br>
-
          </ul>
+
             <a href="https://2011.igem.org/Team:UT_Dallas/ProjectPhototaxis"><img        src="https://static.igem.org/mediawiki/2011/d/d6/Phototaxis.png" width="210" height="43"><br></br>
-
        </div>
+
            <a href="https://2011.igem.org/Team:UT_Dallas/ProjectSuicideMechanism"><img src="
 +
https://static.igem.org/mediawiki/2011/1/16/Suicide_Mechanism.png
-
        <!-- <h2><span></span><font size="5" face="Arial">Explore Our Page!</font></h2>
+
" width="210" height="43"><br></br>
           <div class="clr"></div>
           <div class="clr"></div>
           <ul class="sb_menu">
           <ul class="sb_menu">
-
             <li class="active"><a href="https://2011.igem.org/Team:UT_Dallas"><font size="3" face="verdana">Home</a></font></li>
+
              
-
            <li><a href="https://2011.igem.org/Team:UT_Dallas/Team"><font size="3" face="verdana">Project</a></font></li>
+
-
            <li><a href="#"><font size="3" face="verdana">Team</a></font></li>
+
-
 
+
-
            <li><a href="#"><font size="3" face="verdana"><font size="3" face="verdana">Protocols</a></font></li>
+
-
            <li><a href="#"><font size="3" face="verdana">Parts</a></font></li>
+
-
            <li><a href="#"><font size="3" face="verdana">Modeling</a></font></li>
+
-
            <li><a href="#"><font size="3" face="verdana">Notebook</a></font></li>
+
-
 
+
-
            <li><a href="#"><font size="3" face="verdana">Human Practices</a></font></li>
+
-
            <li><a href="#"><font size="3" face="verdana">Gallery</a></font></li>
+
           </ul>
           </ul>
         </div>
         </div>
-
                <div class="gadget">
+
                      <div class="gadget">
-
          <h2 class="grey"><span>Multimedia</span></h2>
+
       
           <div class="clr"></div>
           <div class="clr"></div>
           <div class="testi">
           <div class="testi">
-
             <p><span class="q"><img src="https://static.igem.org/mediawiki/2011/8/85/Quote_1.gif" width="16" height="14" alt="" /></span> Twitter embed <span class="q"><img src="https://static.igem.org/mediawiki/2011/a/a1/Quote_2.gif" width="16" height="14" alt="" /></span></p>
+
              
-
   
+
                </div>
-
          </div>
+
         </div>
         </div>
       </div>
       </div>
Line 518: Line 499:
" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/e/e8/Pic_3.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/2/2a/Pic_4.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/1/17/Pic_5.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/7/76/Pic_6.jpg" width="58" height="58" alt="" /></a> </div>
" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/e/e8/Pic_3.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/2/2a/Pic_4.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/1/17/Pic_5.jpg" width="58" height="58" alt="" /></a> <a href="#"><img src="https://static.igem.org/mediawiki/2011/7/76/Pic_6.jpg" width="58" height="58" alt="" /></a> </div>
     <div class="col c2">
     <div class="col c2">
-
       <h2><span><font size="5" face="verdana">UT Dallas</span></font></h2>
+
       <h2><span><font size="5" face="arial">UT Dallas</span></font></h2>
-
 
+
    <img src="https://static.igem.org/mediawiki/2011/a/ad/Nserl_Pic.png" width="112" height="138" alt="" ALIGN = RIGHT />   
-
      <p><br />
+
<p>
-
      </p><p><a href="#"><font size="3" face="verdana">Click here to learn more about UTD</a></font></p>
+
      </font></p><p><a href="https://2011.igem.org/Team:UT_Dallas/UTDallas"><font size="3" face="verdana">Click here to learn more&nbsp; about UTD</a></font></p>
     </div>
     </div>
     <div class="col c3">
     <div class="col c3">
-
       <h2><span><font size="5" face="verdana">Notebook</span></font></h2>
+
       <h2><span><font size="5" face="arial">Notebook</span></font></h2>
-
       <p></p><p> <a href="#"><font size="3" face="verdana">Learn more...</a></font></p>
+
       <p>
 +
</p><p> <a href="https://2011.igem.org/Team:UT_Dallas/Notebook"><font size="3" face="verdana">Learn more...</a></font></p>
     </div>
     </div>
Line 532: Line 514:
   <div class="footer">
   <div class="footer">
     <div class="footer_resize">
     <div class="footer_resize">
-
      <p class="lf">&copy; Copyright <a href="#">MyWebSite</a>.</p>
+
 
-
       <p class="rf">Layout by Cool <a href="http://www.coolwebtemplates.net/">Website Templates</a></p>
+
    <!-- <p class="lf">&copy; Copyright <a href="#">MyWebSite</a>.</p>
 +
       <p class="rf">Layout by Cool <a href="http://www.coolwebtemplates.net/">Website Templates</a></p>-->
       <div class="clr"></div>
       <div class="clr"></div>

Latest revision as of 23:59, 5 September 2011

biz solution

Overview

The human bowel hosts a rich diversity of symbiotic microflora that provides a powerful engineering platform for intelligent probiotics. These “immunobots” will ideally work in-sync and enhance natural self-repair mechanisms for a range of intestinal diseases associated with tissue damage. Towards this end, we engineered a bacterial chemotaxis pathway that utilizes a chimeric receptor to successfully interface with the immune system. In addition, we introduced an inducible secondary bacterial population that can trigger system-wide self-destruction, conferring an additional level of user control. Each module of our system was characterized using fluorescent reporters and the integrated parts were evaluated by controlled experiments involving wound signal gradients. We envision a probiotic solution that can facilitate localized tissue repair for damage resulting from inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease.













Subprojects







Image Gallery

UT Dallas

Click here to learn more  about UTD

Notebook

Learn more...

Retrieved from "http://2011.igem.org/Team:UT_Dallas/Project"