GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.215 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0347 PROTEIN_ASSOCIATION: MhpA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0347 PROTEIN_ASSOCIATION: MhpA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0004 PROTEIN_ASSOCIATION: ThrC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4266 PROTEIN_ASSOCIATION: IdnO SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.69 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2836 PROTEIN_ASSOCIATION: Aas SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2836 PROTEIN_ASSOCIATION: Aas SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2836 PROTEIN_ASSOCIATION: Aas SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2836 PROTEIN_ASSOCIATION: Aas SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2836 PROTEIN_ASSOCIATION: Aas SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3793 PROTEIN_ASSOCIATION: WecF SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2901 PROTEIN_ASSOCIATION: BglA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.86 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2662 or b1302 ) PROTEIN_ASSOCIATION: ( GabT ) or ( PuuE ) SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2663 PROTEIN_ASSOCIATION: GabP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2221 and b2222 ) PROTEIN_ASSOCIATION: AtoADec SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2224 PROTEIN_ASSOCIATION: AtoBec SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2223 PROTEIN_ASSOCIATION: AtoE SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0351 PROTEIN_ASSOCIATION: MhpF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1993 PROTEIN_ASSOCIATION: CobU SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0185 and b2316 and b3255 and b3256 ) PROTEIN_ASSOCIATION: Acc SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 6.4.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0335 PROTEIN_ASSOCIATION: PrpE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 6.2.1.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3784 PROTEIN_ASSOCIATION: WecA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0679 and b2415 and b2416 ) or ( b2417 and b1101 and b2415 and b2416 ) ) PROTEIN_ASSOCIATION: ( NagE and PtsH and PtsI ) or ( Crr and PtsG and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3959 PROTEIN_ASSOCIATION: ArgB SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.2.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2818 PROTEIN_ASSOCIATION: ArgA SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) ) PROTEIN_ASSOCIATION: ( IlvB ) or ( IlvG ) or ( IlvH ) SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2296 or b1849 or b3115 ) PROTEIN_ASSOCIATION: ( AckA ) or ( PurT ) or ( TdcD ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 2.7.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3670 and b3671 ) or ( b3767 and b3768 and b3769 ) or ( b0077 and b0078 ) ) PROTEIN_ASSOCIATION: ( IlvB ) or ( IlvG ) or ( IlvH ) SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.1.3.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3794 PROTEIN_ASSOCIATION: WecG SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3224 PROTEIN_ASSOCIATION: NanT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3225 PROTEIN_ASSOCIATION: NanA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1091 PROTEIN_ASSOCIATION: FabHec SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.38 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3957 PROTEIN_ASSOCIATION: ArgE SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1519 PROTEIN_ASSOCIATION: Tam SUBSYSTEM: S_Unassigned PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1276 or b0118 ) PROTEIN_ASSOCIATION: ( AcnA ) or ( AcnB ) SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 4.2.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3359 PROTEIN_ASSOCIATION: ArgD SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2563 PROTEIN_ASSOCIATION: AcpS SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.8.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4069 PROTEIN_ASSOCIATION: Acs SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 6.2.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1623 PROTEIN_ASSOCIATION: Add SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1096 PROTEIN_ASSOCIATION: PabC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3360 and b1812 ) PROTEIN_ASSOCIATION: ( PabA and PabBec ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3665 PROTEIN_ASSOCIATION: YicP SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3654 PROTEIN_ASSOCIATION: YicE SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1241 PROTEIN_ASSOCIATION: AdhE SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0474 PROTEIN_ASSOCIATION: Adk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0474 PROTEIN_ASSOCIATION: Adk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0474 PROTEIN_ASSOCIATION: Adk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0120 PROTEIN_ASSOCIATION: SpeD SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.50 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3806 PROTEIN_ASSOCIATION: CyaA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 4.6.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0474 PROTEIN_ASSOCIATION: Adk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1993 PROTEIN_ASSOCIATION: CobU SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1992 PROTEIN_ASSOCIATION: CobS SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0469 PROTEIN_ASSOCIATION: Apt SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2750 PROTEIN_ASSOCIATION: CysC SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 2.7.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1131 PROTEIN_ASSOCIATION: PurB SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.3.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1131 PROTEIN_ASSOCIATION: PurB SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.3.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4177 PROTEIN_ASSOCIATION: PurA SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0677 PROTEIN_ASSOCIATION: NagA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.5.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3619 PROTEIN_ASSOCIATION: RfaD SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.3.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2937 PROTEIN_ASSOCIATION: SpeB SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.3.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3958 PROTEIN_ASSOCIATION: ArgC SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.38 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 3.3.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0159 PROTEIN_ASSOCIATION: Mtn SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 3.2.2.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4006 PROTEIN_ASSOCIATION: PurH SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0522 PROTEIN_ASSOCIATION: PurK SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0523 PROTEIN_ASSOCIATION: PurE SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0116 and b0726 and b0727 ) PROTEIN_ASSOCIATION: ( LpdA and SucAec and SucBec ) SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2587 PROTEIN_ASSOCIATION: KgtPec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0381 or b0092 ) PROTEIN_ASSOCIATION: ( DdlA ) or ( DdlB ) SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4053 PROTEIN_ASSOCIATION: Alrec SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 5.1.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1190 PROTEIN_ASSOCIATION: DadX SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 5.1.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2551 PROTEIN_ASSOCIATION: GlyA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.6.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2551 PROTEIN_ASSOCIATION: GlyA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 ) PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0007 or b4208 ) PROTEIN_ASSOCIATION: ( YaaJ ) or ( CycAec ) SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0356 PROTEIN_ASSOCIATION: AdhC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1385 PROTEIN_ASSOCIATION: FeaB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.39 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1300 PROTEIN_ASSOCIATION: AldH SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0516 PROTEIN_ASSOCIATION: AllC SUBSYSTEM: S_Nitrogen_Metabolism PROTEIN_CLASS: 3.5.3.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0512 PROTEIN_ASSOCIATION: AllB SUBSYSTEM: S_Nitrogen_Metabolism PROTEIN_CLASS: 3.5.2.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0511 PROTEIN_ASSOCIATION: AllP SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3091 PROTEIN_ASSOCIATION: UxaA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3416 PROTEIN_ASSOCIATION: MalQ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3416 PROTEIN_ASSOCIATION: MalQ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3416 PROTEIN_ASSOCIATION: MalQ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3416 PROTEIN_ASSOCIATION: MalQ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3223 PROTEIN_ASSOCIATION: NanE SUBSYSTEM: S_Putative PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3222 PROTEIN_ASSOCIATION: NanK SUBSYSTEM: S_Putative PROTEIN_CLASS: 2.7.1.60 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0774 PROTEIN_ASSOCIATION: BioAec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.6.1.62 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3929 PROTEIN_ASSOCIATION: MenG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3994 PROTEIN_ASSOCIATION: ThiC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1982 PROTEIN_ASSOCIATION: Amn SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.2.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1263 PROTEIN_ASSOCIATION: TrpDec SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.4.2.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1263 and b1264 ) PROTEIN_ASSOCIATION: ( TrpDec and TrpEec ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.3.27 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0776 PROTEIN_ASSOCIATION: BioF SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.3.1.47 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0049 PROTEIN_ASSOCIATION: ApaH SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.41 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0049 PROTEIN_ASSOCIATION: ApaH SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0414 PROTEIN_ASSOCIATION: RibDec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.193 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0062 PROTEIN_ASSOCIATION: AraA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1901 and b1900 and ( b1898 and b1899 ) ) PROTEIN_ASSOCIATION: ( AraF and AraG and AraH ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2841 PROTEIN_ASSOCIATION: AraE SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2938 or b4117 ) PROTEIN_ASSOCIATION: ( SpeA ) or ( AdiA ) SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1605 PROTEIN_ASSOCIATION: ArcD SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3960 PROTEIN_ASSOCIATION: ArgH SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.3.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3172 PROTEIN_ASSOCIATION: ArgG SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.4.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2310 and b2307 and b2306 and b2308 ) or ( b0860 and b0861 and b0864 and b0862 ) ) PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ ) or ( ArtJ and ArtM and ArtP and ArtQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3433 PROTEIN_ASSOCIATION: Asd SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.2.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1767 or b2957 or b0828 ) PROTEIN_ASSOCIATION: ( AnsA ) or ( AnsB ) or ( YbiK ) SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 3.5.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0674 PROTEIN_ASSOCIATION: AsnB SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 6.3.5.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3744 PROTEIN_ASSOCIATION: AsnA SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 6.3.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0131 PROTEIN_ASSOCIATION: PanD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4244 and b4245 ) PROTEIN_ASSOCIATION: PyrBec SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.3.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0002 or b3940 or b4024 ) PROTEIN_ASSOCIATION: ( ThrA ) or ( MetL ) or ( LysCec ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.7.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2574 PROTEIN_ASSOCIATION: NadB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2574 PROTEIN_ASSOCIATION: NadB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2574 PROTEIN_ASSOCIATION: NadB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2574 PROTEIN_ASSOCIATION: NadB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4139 PROTEIN_ASSOCIATION: AspA SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 4.3.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0928 PROTEIN_ASSOCIATION: AspC SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.6.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0655 and b0654 and b0653 and b0652 ) PROTEIN_ASSOCIATION: ( GltI and GltJ and GltK and GltL ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4077 PROTEIN_ASSOCIATION: GltP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3528 PROTEIN_ASSOCIATION: DctA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4138 or b4123 ) PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1747 PROTEIN_ASSOCIATION: AstA SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.109 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Unassigned PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2019 PROTEIN_ASSOCIATION: HisG SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.4.2.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3736 and b3737 and b3738 ) and ( b3731 and b3732 and b3733 and b3734 and b3735 ) and b3739 ) PROTEIN_ASSOCIATION: ( AtpF0 and AtpF1 and AtpI ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 3.6.3.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0312 PROTEIN_ASSOCIATION: BetB SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 1.2.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0312 PROTEIN_ASSOCIATION: BetB SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 1.2.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 3.1.3.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3551 PROTEIN_ASSOCIATION: BisC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3551 PROTEIN_ASSOCIATION: BisC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0775 PROTEIN_ASSOCIATION: BioBec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2221 and b2222 ) PROTEIN_ASSOCIATION: AtoADec SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.8.3.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2223 PROTEIN_ASSOCIATION: AtoE SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0954 and b2323 and b1093 and b1288 and b0180 ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI and FabZ ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0954 and b2323 and b1093 and b1288 ) or ( b2323 and b1093 and b1288 and b0180 ) or ( b1095 and b1093 and b1288 and b0180 ) or ( b0954 and b1095 and b1093 and b1288 ) ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI ) or ( FabB and FabGec and FabI and FabZ ) or ( FabF and FabGec and FabI and FabZ ) or ( FabA and FabF and FabGec and FabI ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0954 and b2323 and b1093 and b1288 and b0180 ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabGec and FabI and FabZ ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0954 and b2323 and b1095 and b1093 and b1288 and b0180 ) PROTEIN_ASSOCIATION: ( FabA and FabB and FabF and FabGec and FabI and FabZ ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4132 PROTEIN_ASSOCIATION: CadB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1732 or b3942 ) PROTEIN_ASSOCIATION: ( KatE ) or ( KatG ) SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 1.11.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1270 PROTEIN_ASSOCIATION: BtuR SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3966 and b1711 and b1709 and b0158 ) PROTEIN_ASSOCIATION: ( BtuB and BtuC and BtuD and BtuF ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1270 PROTEIN_ASSOCIATION: BtuR SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0521 or b2874 or b0323 ) PROTEIN_ASSOCIATION: ( ArcCec ) or ( YqeA ) or ( YahI ) SUBSYSTEM: S_Putative PROTEIN_CLASS: 2.7.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0032 and b0033 ) PROTEIN_ASSOCIATION: Car SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.5.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3918 PROTEIN_ASSOCIATION: Cdhec SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 3.6.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1208 PROTEIN_ASSOCIATION: IspE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2128 and b2129 and b2130 and b2131 ) PROTEIN_ASSOCIATION: ( YehW and YehX and YehY and YehZ ) SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0314 or b1801 ) PROTEIN_ASSOCIATION: ( BetT ) or ( YeaV ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2599 or b2600 ) PROTEIN_ASSOCIATION: ( PheA ) or ( TyrAec ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.4.99.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2329 PROTEIN_ASSOCIATION: AroC SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4039 PROTEIN_ASSOCIATION: UbiC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2538 and b2539 and b2540 and b2542 ) PROTEIN_ASSOCIATION: HcaCDEF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0615 and b0616 and b0617 ) PROTEIN_ASSOCIATION: CitDEF SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 4.1.3.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0612 PROTEIN_ASSOCIATION: CitT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1249 PROTEIN_ASSOCIATION: Cls SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.2.2.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2436 PROTEIN_ASSOCIATION: HemF SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.3.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0038 PROTEIN_ASSOCIATION: CaiB SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0038 PROTEIN_ASSOCIATION: CaiB SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0036 PROTEIN_ASSOCIATION: CaiD SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0040 PROTEIN_ASSOCIATION: CaiT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0720 PROTEIN_ASSOCIATION: GltA SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0337 PROTEIN_ASSOCIATION: CodA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0336 PROTEIN_ASSOCIATION: CodB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2780 PROTEIN_ASSOCIATION: PyrG SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3425 PROTEIN_ASSOCIATION: GlpE SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 2.8.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0340 PROTEIN_ASSOCIATION: CynS SUBSYSTEM: S_Nitrogen_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0341 PROTEIN_ASSOCIATION: CynX SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3708 PROTEIN_ASSOCIATION: TnaA SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 4.1.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2414 or b2421 ) PROTEIN_ASSOCIATION: ( CysKec ) or ( CysM ) SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3008 or b1622 ) PROTEIN_ASSOCIATION: ( MetC ) or ( MalY ) SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.4.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0733 and b0734 ) PROTEIN_ASSOCIATION: CydA SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0429 and b0430 and b0431 and b0432 ) PROTEIN_ASSOCIATION: CyoA SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2143 PROTEIN_ASSOCIATION: Cdd SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2066 PROTEIN_ASSOCIATION: Udk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0910 PROTEIN_ASSOCIATION: Cmk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0910 PROTEIN_ASSOCIATION: Cmk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1189 PROTEIN_ASSOCIATION: DadA SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 1.4.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1623 PROTEIN_ASSOCIATION: Add SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0474 PROTEIN_ASSOCIATION: Adk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4042 PROTEIN_ASSOCIATION: DgkA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.1.107 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4208 PROTEIN_ASSOCIATION: CycAec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2838 PROTEIN_ASSOCIATION: LysA SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3809 PROTEIN_ASSOCIATION: DapF SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 5.1.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0175 PROTEIN_ASSOCIATION: CdsA SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.7.7.41 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3041 PROTEIN_ASSOCIATION: RibBec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0778 PROTEIN_ASSOCIATION: BioDec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2065 PROTEIN_ASSOCIATION: Dcd SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2143 PROTEIN_ASSOCIATION: Cdd SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3693 PROTEIN_ASSOCIATION: DgoK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.58 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3909 PROTEIN_ASSOCIATION: KdgT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3526 PROTEIN_ASSOCIATION: KdgK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.45 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2601 or b0754 or b1704 ) PROTEIN_ASSOCIATION: ( AroF ) or ( AroGec ) or ( AroH ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.2.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3692 PROTEIN_ASSOCIATION: DgoA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3648 PROTEIN_ASSOCIATION: Gmkec SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2964 PROTEIN_ASSOCIATION: NupG SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3771 PROTEIN_ASSOCIATION: IlvD SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.2.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3771 PROTEIN_ASSOCIATION: IlvD SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1200 and b1199 and b1198 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( DhaK and DhaL and DhaM and PtsH and PtsI ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0596 PROTEIN_ASSOCIATION: EntA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.3.1.28 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0594 PROTEIN_ASSOCIATION: EntE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.58 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2541 PROTEIN_ASSOCIATION: HcaB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0348 PROTEIN_ASSOCIATION: MhpB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0031 PROTEIN_ASSOCIATION: DapB SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.3.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2478 PROTEIN_ASSOCIATION: DapA SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.2.1.52 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0048 PROTEIN_ASSOCIATION: FolA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.5.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2315 PROTEIN_ASSOCIATION: FolCec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3930 PROTEIN_ASSOCIATION: MenA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3058 PROTEIN_ASSOCIATION: FolB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0945 PROTEIN_ASSOCIATION: PyrD SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0945 PROTEIN_ASSOCIATION: PyrD SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.3.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1062 PROTEIN_ASSOCIATION: PyrC SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2541 PROTEIN_ASSOCIATION: HcaB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0414 PROTEIN_ASSOCIATION: RibDec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.4.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3177 PROTEIN_ASSOCIATION: FolP SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1693 PROTEIN_ASSOCIATION: AroD SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3389 PROTEIN_ASSOCIATION: AroB SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2964 PROTEIN_ASSOCIATION: NupG SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0207 or b3012 ) PROTEIN_ASSOCIATION: ( DkgB ) or ( DkgA ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3553 PROTEIN_ASSOCIATION: YiaE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0421 PROTEIN_ASSOCIATION: IspA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0029 PROTEIN_ASSOCIATION: LytB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2232 PROTEIN_ASSOCIATION: UbiG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0894 and b0895 and b0896 ) PROTEIN_ASSOCIATION: DmsABC SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1873 and b1872 ) PROTEIN_ASSOCIATION: ( TorY and TorZ ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0894 and b0895 and b0896 ) PROTEIN_ASSOCIATION: DmsABC SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1873 and b1872 ) PROTEIN_ASSOCIATION: ( TorY and TorZ ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1865 or b0099 ) PROTEIN_ASSOCIATION: ( NtpA ) or ( MutT ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3575 PROTEIN_ASSOCIATION: YiaK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.24 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0425 or b3774 ) PROTEIN_ASSOCIATION: ( PanE ) or ( IlvCec ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.1.1.169 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4381 PROTEIN_ASSOCIATION: DeoC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4208 PROTEIN_ASSOCIATION: CycAec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1098 PROTEIN_ASSOCIATION: Tmk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1238 PROTEIN_ASSOCIATION: Tdk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4382 or b4384 ) PROTEIN_ASSOCIATION: ( DeoA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3640 PROTEIN_ASSOCIATION: Dutec SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.6.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0173 PROTEIN_ASSOCIATION: Dxr SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0420 PROTEIN_ASSOCIATION: Dxs SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3564 PROTEIN_ASSOCIATION: XylB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3603 or b2975 ) PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2927 PROTEIN_ASSOCIATION: Epd SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1850 PROTEIN_ASSOCIATION: Eda SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 4.1.2.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1851 PROTEIN_ASSOCIATION: Edd SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 4.2.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1054 PROTEIN_ASSOCIATION: LpxL SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1855 PROTEIN_ASSOCIATION: MsbB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2378 PROTEIN_ASSOCIATION: LpxP SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1855 PROTEIN_ASSOCIATION: MsbB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2779 PROTEIN_ASSOCIATION: Eno SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.2.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0583 PROTEIN_ASSOCIATION: EntD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2440 and b2441 ) PROTEIN_ASSOCIATION: EutBC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 4.3.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_ PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0825 or b3946 ) PROTEIN_ASSOCIATION: ( Fsa ) or ( TalC ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 ) PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 ) PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3845 and b3846 and b1805 and b0221 ) PROTEIN_ASSOCIATION: ( FadA and FadB and FadD and FadE ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3846 and b0221 ) PROTEIN_ASSOCIATION: ( FadB and FadE ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2925 or b2097 or b1773 ) PROTEIN_ASSOCIATION: ( FbaA ) or ( FbaB ) or ( B1773 ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 4.1.2.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4232 PROTEIN_ASSOCIATION: Fbp SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 3.1.3.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2802 PROTEIN_ASSOCIATION: FucI SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2803 PROTEIN_ASSOCIATION: FucK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.51 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2800 or b2738 ) PROTEIN_ASSOCIATION: ( FucA ) or ( YgbL ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0475 PROTEIN_ASSOCIATION: HemH SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.99.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b1474 and b1475 and b1476 ) or ( b3892 and b3893 and b3894 ) or b4079 ) PROTEIN_ASSOCIATION: ( Fdn ) or ( Fdoec ) or ( FdhF ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.2.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3892 and b3893 and b3894 ) or ( b1474 and b1475 and b1476 ) ) PROTEIN_ASSOCIATION: ( Fdoec ) or ( Fdn ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.2.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3409 PROTEIN_ASSOCIATION: FeoB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4079 and ( b2719 and b2720 and b2721 and b2722 and b2723 and b2724 ) ) PROTEIN_ASSOCIATION: ( FdhF and HycB ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0025 PROTEIN_ASSOCIATION: RibFec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0904 or b2492 ) PROTEIN_ASSOCIATION: ( FocA ) or ( FocB ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4151 and b4152 and b4153 and b4154 ) PROTEIN_ASSOCIATION: Frd SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.3.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4151 and b4152 and b4153 and b4154 ) PROTEIN_ASSOCIATION: Frd SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.3.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2168 PROTEIN_ASSOCIATION: FruK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.56 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2167 and b2169 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( FruAec and FruBec and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1232 PROTEIN_ASSOCIATION: PurUec SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 3.5.1.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3666 PROTEIN_ASSOCIATION: UhpT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2801 PROTEIN_ASSOCIATION: FucP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1612 or b4122 or b1611 ) PROTEIN_ASSOCIATION: ( FumA ) or ( FumB ) or ( FumCec ) SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 4.2.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3528 PROTEIN_ASSOCIATION: DctA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4138 or b4123 or b0621 ) PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) or ( DcuC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3730 PROTEIN_ASSOCIATION: GlmUec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.3.1.157 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1002 PROTEIN_ASSOCIATION: Agp SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 3.1.3.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2039 or b3789 ) PROTEIN_ASSOCIATION: ( RfbA ) or ( RffH ) SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.24 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0154 PROTEIN_ASSOCIATION: HemLec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 5.4.3.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3608 PROTEIN_ASSOCIATION: GpsA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.94 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2241 and b2242 and b2243 ) or b3426 ) PROTEIN_ASSOCIATION: ( GlpA ) or ( GlpD ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.1.99.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2241 and b2242 and b2243 ) PROTEIN_ASSOCIATION: GlpA SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.1.99.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2241 and b2242 and b2243 ) PROTEIN_ASSOCIATION: GlpA SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.1.99.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0243 PROTEIN_ASSOCIATION: ProA SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.41 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0678 PROTEIN_ASSOCIATION: NagB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.5.99.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1852 PROTEIN_ASSOCIATION: Zwf SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 1.1.1.49 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3666 PROTEIN_ASSOCIATION: UhpT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3128 PROTEIN_ASSOCIATION: GarD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3692 PROTEIN_ASSOCIATION: DgoA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3691 PROTEIN_ASSOCIATION: DgoT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3127 PROTEIN_ASSOCIATION: GarP SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0757 or b2045 ) PROTEIN_ASSOCIATION: ( GalK ) or ( WcaK ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4119 PROTEIN_ASSOCIATION: MelA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2094 and b2093 and b2092 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( GatA and GatB and GatC and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1236 PROTEIN_ASSOCIATION: GalUec SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.7.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3093 PROTEIN_ASSOCIATION: ExuT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1236 or b2042 ) PROTEIN_ASSOCIATION: ( GalUec ) or ( GalF ) SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2149 and b2150 and b2148 ) PROTEIN_ASSOCIATION: ( MglA and MglB and MglC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2943 PROTEIN_ASSOCIATION: GalP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1779 or ( b1416 and b1417 ) ) PROTEIN_ASSOCIATION: ( GapA ) or ( GapC ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 1.2.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2500 PROTEIN_ASSOCIATION: PurN SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.1.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1849 PROTEIN_ASSOCIATION: PurT SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1415 PROTEIN_ASSOCIATION: AldA SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.2.1.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2052 PROTEIN_ASSOCIATION: Fcl SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3729 PROTEIN_ASSOCIATION: GlmS SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.6.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2551 PROTEIN_ASSOCIATION: GlyA SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.1.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3648 PROTEIN_ASSOCIATION: Gmkec SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0124 PROTEIN_ASSOCIATION: Gcd SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4265 or b4321 or b3415 ) PROTEIN_ASSOCIATION: ( IdnT ) or ( GntP ) or ( GntT ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3428 or b3417 ) PROTEIN_ASSOCIATION: ( GlgP ) or ( MalP ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.4.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3126 PROTEIN_ASSOCIATION: GarL SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2787 or b2788 ) PROTEIN_ASSOCIATION: ( GudD ) or ( YgcY ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.40 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3127 or b2789 ) PROTEIN_ASSOCIATION: ( GarP ) or ( GudP ) SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3429 PROTEIN_ASSOCIATION: GlgA SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.4.1.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3093 or b3909 ) PROTEIN_ASSOCIATION: ( ExuT ) or ( KdgT ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2417 and b1101 and b2415 and b2416 ) or ( b2417 and b1621 and b2415 and b2416 ) or ( b1817 and b1818 and b1819 and b2415 and b2416 ) ) PROTEIN_ASSOCIATION: ( Crr and PtsG and PtsH and PtsI ) or ( Crr and MalX and PtsH and PtsI ) or ( ManX and ManY and ManZ and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2943 PROTEIN_ASSOCIATION: GalP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3430 PROTEIN_ASSOCIATION: GlgC SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.7.27 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3870 or b1297 ) PROTEIN_ASSOCIATION: ( GlnA ) or ( YcjK ) SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 6.3.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0811 and b0810 and b0809 ) PROTEIN_ASSOCIATION: ( GlnHec and GlnPec and GlnQec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2091 PROTEIN_ASSOCIATION: GatD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0242 PROTEIN_ASSOCIATION: ProB SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.2.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1492 PROTEIN_ASSOCIATION: XasA SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2688 PROTEIN_ASSOCIATION: GshA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3517 or b1493 ) PROTEIN_ASSOCIATION: ( GadA ) or ( GadB ) SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 4.1.1.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1761 PROTEIN_ASSOCIATION: GdhA SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.4.1.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1812 or b0485 or b1524 or b2957 ) PROTEIN_ASSOCIATION: ( PabBec ) or ( YbaS ) or ( YneH ) or ( AnsB ) SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 3.5.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2312 PROTEIN_ASSOCIATION: PurF SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3967 PROTEIN_ASSOCIATION: MurI SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3212 and b3213 ) PROTEIN_ASSOCIATION: GltB SUBSYSTEM: S_Glutamate_metabolism PROTEIN_CLASS: 1.4.1.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1210 PROTEIN_ASSOCIATION: HemA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2400 PROTEIN_ASSOCIATION: GltX SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.1.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0655 and b0654 and b0653 and b0652 ) PROTEIN_ASSOCIATION: ( GltI and GltJ and GltK and GltL ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4077 PROTEIN_ASSOCIATION: GltP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3653 PROTEIN_ASSOCIATION: GltS SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0507 PROTEIN_ASSOCIATION: Gcl SUBSYSTEM: S_Glyoxylate_Metabolism PROTEIN_CLASS: 4.1.1.47 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3927 PROTEIN_ASSOCIATION: GlpF SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3617 PROTEIN_ASSOCIATION: Kbl SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.3.1.29 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2128 and b2129 and b2130 and b2131 ) PROTEIN_ASSOCIATION: ( YehW and YehX and YehY and YehZ ) SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1801 PROTEIN_ASSOCIATION: YeaV SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3452 and b3453 and b3450 and b3451 ) PROTEIN_ASSOCIATION: ( UgpA and UgpB and UgpC and UgpE ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2240 PROTEIN_ASSOCIATION: GlpT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3945 PROTEIN_ASSOCIATION: GldA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0514 or b3124 ) PROTEIN_ASSOCIATION: ( GlxK ) or ( GarK ) SUBSYSTEM: S_Glyoxylate_Metabolism PROTEIN_CLASS: 2.7.1.31 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2904 and b2903 and b2905 and b0116 ) PROTEIN_ASSOCIATION: ( GcvH and GcvP and GcvT and LpdA ) SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3553 or b1033 ) PROTEIN_ASSOCIATION: ( YiaE ) or ( YcdW ) SUBSYSTEM: S_Glyoxylate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1033 or b3553 ) PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE ) SUBSYSTEM: S_Glyoxylate_Metabolism PROTEIN_CLASS: 1.1.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3603 or b2975 ) PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2978 and b2979 ) PROTEIN_ASSOCIATION: GlcDF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2978 and b2979 ) PROTEIN_ASSOCIATION: GlcDF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2978 and b2979 ) PROTEIN_ASSOCIATION: GlcDF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3927 PROTEIN_ASSOCIATION: GlpF SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3926 PROTEIN_ASSOCIATION: GlpK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.30 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0212 PROTEIN_ASSOCIATION: GloB SUBSYSTEM: S_Methylglyoxal_Metabolism PROTEIN_CLASS: 3.1.2.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4208 or b1801 or b0007 ) PROTEIN_ASSOCIATION: ( CycAec ) or ( YeaV ) or ( YaaJ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2053 PROTEIN_ASSOCIATION: Gmd SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 4.2.1.47 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3052 PROTEIN_ASSOCIATION: RfaEec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3052 PROTEIN_ASSOCIATION: RfaEec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0200 PROTEIN_ASSOCIATION: GmhB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0104 PROTEIN_ASSOCIATION: GuaC SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.7.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2507 PROTEIN_ASSOCIATION: GuaA SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.5.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2029 PROTEIN_ASSOCIATION: Gnd SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 1.1.1.44 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4268 or b3437 ) PROTEIN_ASSOCIATION: ( IdnK ) or ( GntK ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2052 PROTEIN_ASSOCIATION: Fcl SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0049 PROTEIN_ASSOCIATION: ApaH SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2239 PROTEIN_ASSOCIATION: GlpQ SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2239 PROTEIN_ASSOCIATION: GlpQ SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2239 PROTEIN_ASSOCIATION: GlpQ SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2239 PROTEIN_ASSOCIATION: GlpQ SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2239 PROTEIN_ASSOCIATION: GlpQ SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.4.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0421 PROTEIN_ASSOCIATION: IspA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0477 PROTEIN_ASSOCIATION: Gsk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2964 PROTEIN_ASSOCIATION: NupG SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2988 PROTEIN_ASSOCIATION: Gsp SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.5.1.78 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2988 PROTEIN_ASSOCIATION: Gsp SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 6.3.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3500 PROTEIN_ASSOCIATION: GAPOR SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.8.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2947 PROTEIN_ASSOCIATION: GshB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1277 PROTEIN_ASSOCIATION: RibA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2153 PROTEIN_ASSOCIATION: FolE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.4.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2883 PROTEIN_ASSOCIATION: YgfP SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.5.4.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0238 or b0125 ) PROTEIN_ASSOCIATION: ( Gpt ) or ( Hpt ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3654 PROTEIN_ASSOCIATION: YicE SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3092 PROTEIN_ASSOCIATION: UxaC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3092 PROTEIN_ASSOCIATION: UxaC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4040 PROTEIN_ASSOCIATION: UbiA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0353 PROTEIN_ASSOCIATION: MhpT SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0339 or b0126 ) PROTEIN_ASSOCIATION: ( CynT ) or ( YadF ) SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 4.2.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2344 PROTEIN_ASSOCIATION: FadL SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0428 PROTEIN_ASSOCIATION: CyoE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2104 PROTEIN_ASSOCIATION: ThiMec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.50 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2388 PROTEIN_ASSOCIATION: Glk SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2020 PROTEIN_ASSOCIATION: HisD SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 1.1.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2022 PROTEIN_ASSOCIATION: HisB SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.1.3.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2309 and b2307 and b2306 and b2308 ) PROTEIN_ASSOCIATION: ( HisJ and HisM and HisP and HisQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0112 PROTEIN_ASSOCIATION: AroP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0349 PROTEIN_ASSOCIATION: MhpC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0349 PROTEIN_ASSOCIATION: MhpC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3805 PROTEIN_ASSOCIATION: HemCec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.3.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2103 or b2418 ) PROTEIN_ASSOCIATION: ( ThiDec ) or ( PdxK ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.49 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0352 PROTEIN_ASSOCIATION: MhpE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0142 PROTEIN_ASSOCIATION: FolK SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0348 PROTEIN_ASSOCIATION: MhpB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.13.11.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0353 PROTEIN_ASSOCIATION: MhpT SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0508 PROTEIN_ASSOCIATION: Hyi SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1033 or b3553 ) PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1033 or b3553 ) PROTEIN_ASSOCIATION: ( YcdW ) or ( YiaE ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3940 or b0002 ) PROTEIN_ASSOCIATION: ( MetL ) or ( ThrA ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 1.1.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0003 PROTEIN_ASSOCIATION: ThrB SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.7.1.39 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4013 PROTEIN_ASSOCIATION: MetA SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 2.3.1.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2021 PROTEIN_ASSOCIATION: HisC SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.6.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0238 or b0125 ) PROTEIN_ASSOCIATION: ( Gpt ) or ( Hpt ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0972 and b0973 and b0974 ) or ( b2994 and b2997 ) or ( b2719 and b2720 and b2721 and b2722 and b2723 and b2724 ) ) PROTEIN_ASSOCIATION: ( HyaA ) or ( HybC ) or ( HycB ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.18.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2994 and b2997 ) or ( b0972 and b0973 and b0974 ) ) PROTEIN_ASSOCIATION: ( HybC ) or ( HyaA ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.18.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0972 and b0973 and b0974 ) or ( b2994 and b2997 ) ) PROTEIN_ASSOCIATION: ( HyaA ) or ( HybC ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.18.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1136 PROTEIN_ASSOCIATION: Icd SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.1.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2265 or b0593 ) PROTEIN_ASSOCIATION: ( MenF ) or ( EntC ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0595 PROTEIN_ASSOCIATION: EntB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.3.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4015 PROTEIN_ASSOCIATION: AceA SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4267 PROTEIN_ASSOCIATION: IdnD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4267 PROTEIN_ASSOCIATION: IdnD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4265 PROTEIN_ASSOCIATION: IdnT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2023 and b2025 ) PROTEIN_ASSOCIATION: HisF SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2022 PROTEIN_ASSOCIATION: HisB SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 4.2.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1262 PROTEIN_ASSOCIATION: TrpCec SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.1.48 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3770 PROTEIN_ASSOCIATION: IlvE SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 2.6.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 ) PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0401 PROTEIN_ASSOCIATION: BrnQ SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4006 PROTEIN_ASSOCIATION: PurH SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 3.5.4.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2508 PROTEIN_ASSOCIATION: GuaB SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 1.1.1.205 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3161 PROTEIN_ASSOCIATION: Mtr SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0477 PROTEIN_ASSOCIATION: Gsk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.73 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2964 PROTEIN_ASSOCIATION: NupG SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2889 PROTEIN_ASSOCIATION: Idi SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 5.3.3.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0029 PROTEIN_ASSOCIATION: LytB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0073 PROTEIN_ASSOCIATION: LeuB SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 1.1.1.85 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0071 and b0072 ) PROTEIN_ASSOCIATION: LeuC SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.2.1.33 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0071 and b0072 ) PROTEIN_ASSOCIATION: LeuC SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.2.1.33 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0074 PROTEIN_ASSOCIATION: LeuA SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 4.1.3.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3774 PROTEIN_ASSOCIATION: IlvCec SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 1.1.1.86 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3774 PROTEIN_ASSOCIATION: IlvCec SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 1.1.1.86 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2323 or b1095 ) PROTEIN_ASSOCIATION: ( FabB ) or ( FabF ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.41 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1091 PROTEIN_ASSOCIATION: FabHec SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2323 and b1093 ) or ( b1095 and b1093 ) ) PROTEIN_ASSOCIATION: ( FabB and FabGec ) or ( FabF and FabGec ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0918 PROTEIN_ASSOCIATION: KdsBec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.38 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.45 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1215 PROTEIN_ASSOCIATION: KdsA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 4.1.2.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4196 or b3581 ) PROTEIN_ASSOCIATION: ( SgaH ) or ( SgbH ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0696 and b0697 and b0698 ) PROTEIN_ASSOCIATION: KdpABC SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1363 or b3849 ) PROTEIN_ASSOCIATION: ( TrkG ) or ( TrkH ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0344 or b2132 ) PROTEIN_ASSOCIATION: ( LacZ ) or ( BglX ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1415 or b3588 or b0356 or b1300 ) PROTEIN_ASSOCIATION: ( AldA ) or ( AldB ) or ( AdhC ) or ( AldH ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1241 PROTEIN_ASSOCIATION: AdhE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.2.1.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2799 PROTEIN_ASSOCIATION: FucO SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.77 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0343 PROTEIN_ASSOCIATION: LacY SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2133 or b1380 ) PROTEIN_ASSOCIATION: ( Dld ) or ( Ldh ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 1.1.1.28 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2133 PROTEIN_ASSOCIATION: Dld SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.1.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3770 or b4054 ) PROTEIN_ASSOCIATION: ( IlvE ) or ( TyrB ) SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 2.6.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3454 and b3455 and b3457 and b3460 and b3456 ) or ( b3454 and b3455 and b3457 and b3458 and b3456 ) ) PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) or ( LivF and LivG and LivH and LivK and LivM ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0401 PROTEIN_ASSOCIATION: BrnQ SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1651 PROTEIN_ASSOCIATION: GloA SUBSYSTEM: S_Methylglyoxal_Metabolism PROTEIN_CLASS: 4.4.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0182 PROTEIN_ASSOCIATION: LpxB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.4.1.182 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3825 PROTEIN_ASSOCIATION: PldB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3621 and b3620 and b3631 and b3627 and b3626 and b3622 ) PROTEIN_ASSOCIATION: ( RfaC and RfaF and RfaG and RfaI and RfaJec and RfaL ) SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0186 or b4131 ) PROTEIN_ASSOCIATION: ( LdcC ) or ( CadA ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.1.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2310 and b2307 and b2306 and b2308 ) PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2156 PROTEIN_ASSOCIATION: LysP SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3605 PROTEIN_ASSOCIATION: LldD SUBSYSTEM: S_ PROTEIN_CLASS: 1.1.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3605 PROTEIN_ASSOCIATION: LldD SUBSYSTEM: S_ PROTEIN_CLASS: 1.1.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3603 or b2975 ) PROTEIN_ASSOCIATION: ( LldP ) or ( GlcA ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3600 PROTEIN_ASSOCIATION: MtlD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2323 PROTEIN_ASSOCIATION: FabB SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4014 or b2976 ) PROTEIN_ASSOCIATION: ( AceB ) or ( GlcB ) SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.3.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 ) PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 ) PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 ) PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 ) PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4036 and b4034 and b4033 and b4032 and b4035 ) PROTEIN_ASSOCIATION: ( LamB and MalE and MalF and MalG and MalK ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2417 and b4036 and b1621 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( Crr and LamB and MalX and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3528 PROTEIN_ASSOCIATION: DctA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4138 or b4123 ) PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2049 PROTEIN_ASSOCIATION: ManC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1613 PROTEIN_ASSOCIATION: ManA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3666 PROTEIN_ASSOCIATION: UhpT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4323 PROTEIN_ASSOCIATION: UxuB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.57 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1817 and b1818 and b1819 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( ManX and ManY and ManZ and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0334 PROTEIN_ASSOCIATION: PrpD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.79 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0331 PROTEIN_ASSOCIATION: PrpB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.3.30 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0333 PROTEIN_ASSOCIATION: PrpC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.3.31 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1092 PROTEIN_ASSOCIATION: FabD SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.3.1.39 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3236 PROTEIN_ASSOCIATION: Mdh SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.1.1.37 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2210 PROTEIN_ASSOCIATION: Mqo SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.1.99.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2210 PROTEIN_ASSOCIATION: Mqo SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.1.99.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1479 PROTEIN_ASSOCIATION: Sfc SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 1.1.1.38 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2463 PROTEIN_ASSOCIATION: Mae SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 1.1.1.40 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2515 PROTEIN_ASSOCIATION: GcpE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2746 PROTEIN_ASSOCIATION: IspF SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4120 PROTEIN_ASSOCIATION: MelB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2747 PROTEIN_ASSOCIATION: IspD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2942 PROTEIN_ASSOCIATION: MetK SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 2.5.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0198 and b0199 and b0197 ) PROTEIN_ASSOCIATION: ( MetI and MetN and MetQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4019 or b3829 ) PROTEIN_ASSOCIATION: ( MetH ) or ( MetE ) SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 2.1.1.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0198 and b0199 and b0197 ) PROTEIN_ASSOCIATION: ( MetI and MetN and MetQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0963 PROTEIN_ASSOCIATION: MgsA SUBSYSTEM: S_Methylglyoxal_Metabolism PROTEIN_CLASS: 4.2.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2533 PROTEIN_ASSOCIATION: SuhB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1276 or b0118 ) PROTEIN_ASSOCIATION: ( AcnA ) or ( AcnB ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.99 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0403 PROTEIN_ASSOCIATION: MalZ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0403 PROTEIN_ASSOCIATION: MalZ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0403 PROTEIN_ASSOCIATION: MalZ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0403 PROTEIN_ASSOCIATION: MalZ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0403 PROTEIN_ASSOCIATION: MalZ SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3417 PROTEIN_ASSOCIATION: MalP SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3417 PROTEIN_ASSOCIATION: MalP SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3417 PROTEIN_ASSOCIATION: MalP SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2919 PROTEIN_ASSOCIATION: YgfG SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.1.41 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2917 PROTEIN_ASSOCIATION: Sbm SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.99.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3599 and b2415 and b2416 ) PROTEIN_ASSOCIATION: ( MtlA and PtsH and PtsI ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4322 PROTEIN_ASSOCIATION: UxuAec SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3633 PROTEIN_ASSOCIATION: KdtA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3633 PROTEIN_ASSOCIATION: KdtA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0134 PROTEIN_ASSOCIATION: PanB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.2.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0159 PROTEIN_ASSOCIATION: Mtn SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 3.2.2.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0529 PROTEIN_ASSOCIATION: FolD SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 3.5.4.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0529 PROTEIN_ASSOCIATION: FolD SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: 1.5.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3941 PROTEIN_ASSOCIATION: MetF SUBSYSTEM: S_Folate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 5.3.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.7.1.100 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3957 PROTEIN_ASSOCIATION: ArgE SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2411 PROTEIN_ASSOCIATION: Lig SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.6.1.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.6.1.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1109 PROTEIN_ASSOCIATION: Ndh SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1109 PROTEIN_ASSOCIATION: Ndh SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 ) PROTEIN_ASSOCIATION: Nuo SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 ) PROTEIN_ASSOCIATION: Nuo SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288 ) PROTEIN_ASSOCIATION: Nuo SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1109 PROTEIN_ASSOCIATION: Ndh SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2615 PROTEIN_ASSOCIATION: YfjB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1740 PROTEIN_ASSOCIATION: NadEec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b1602 and b1603 ) or b3962 ) PROTEIN_ASSOCIATION: ( Pnt ) or ( SthA ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0931 PROTEIN_ASSOCIATION: PncB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.4.2.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1216 PROTEIN_ASSOCIATION: ChaA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1186 PROTEIN_ASSOCIATION: NhaB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0019 PROTEIN_ASSOCIATION: NhaA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2518 PROTEIN_ASSOCIATION: Ndk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0451 PROTEIN_ASSOCIATION: AmtB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0639 PROTEIN_ASSOCIATION: NadD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.2.2.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0751 PROTEIN_ASSOCIATION: PnuCec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: 3.2.2.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1768 PROTEIN_ASSOCIATION: PncA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 3.5.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0639 PROTEIN_ASSOCIATION: NadD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1991 PROTEIN_ASSOCIATION: CobT SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0109 PROTEIN_ASSOCIATION: NadCec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.4.2.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1223 or b3367 ) PROTEIN_ASSOCIATION: ( NarKec ) or ( NirC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1224 and b1225 and b1226 and b1227 ) PROTEIN_ASSOCIATION: NarGHIJ SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.7.99.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1224 and b1225 and b1226 and b1227 ) PROTEIN_ASSOCIATION: NarGHIJ SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1223 or b1469 ) PROTEIN_ASSOCIATION: ( NarKec ) or ( NarU ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2262 PROTEIN_ASSOCIATION: MenB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.3.36 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0099 or b2781 ) PROTEIN_ASSOCIATION: ( MutT ) or ( MazG ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0099 or b2781 ) PROTEIN_ASSOCIATION: ( MutT ) or ( MazG ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2781 PROTEIN_ASSOCIATION: MazG SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0160 PROTEIN_ASSOCIATION: Dgt SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.5.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0160 PROTEIN_ASSOCIATION: Dgt SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 3.1.5.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3365 and b3366 ) PROTEIN_ASSOCIATION: NirBD SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3114 or ( b0902 and b0903 ) ) PROTEIN_ASSOCIATION: ( TdcE ) or ( PflA ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4254 or b0273 ) PROTEIN_ASSOCIATION: ( ArgI ) or ( ArgF ) SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.1.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2344 PROTEIN_ASSOCIATION: FadL SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3187 PROTEIN_ASSOCIATION: IspB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0907 PROTEIN_ASSOCIATION: SerC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.6.1.52 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2232 PROTEIN_ASSOCIATION: UbiG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3833 PROTEIN_ASSOCIATION: UbiE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0073 PROTEIN_ASSOCIATION: LeuB SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0662 PROTEIN_ASSOCIATION: UbiF SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1281 PROTEIN_ASSOCIATION: PyrF SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 4.1.1.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2907 PROTEIN_ASSOCIATION: UbiH SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0350 PROTEIN_ASSOCIATION: MhpD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.80 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3843 or b2311 ) PROTEIN_ASSOCIATION: ( UbiD ) or ( UbiX ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3835 PROTEIN_ASSOCIATION: UbiB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2965 or b0693 ) PROTEIN_ASSOCIATION: ( SpeC ) or ( SpeF ) SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 4.1.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3073 PROTEIN_ASSOCIATION: YgjG SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2310 and b2307 and b2306 and b2308 ) PROTEIN_ASSOCIATION: ( ArgT and HisM and HisP and HisQ ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3642 PROTEIN_ASSOCIATION: PyrE SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 2.4.2.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2264 PROTEIN_ASSOCIATION: MenD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.71 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1014 PROTEIN_ASSOCIATION: PutAec SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0386 PROTEIN_ASSOCIATION: ProC SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1398 PROTEIN_ASSOCIATION: PaaK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 6.2.1.30 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0133 PROTEIN_ASSOCIATION: PanCec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.1.3.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0087 PROTEIN_ASSOCIATION: MraY SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.8.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2762 PROTEIN_ASSOCIATION: CysH SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 1.8.4.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4041 and b3018 ) PROTEIN_ASSOCIATION: ( PlsBec and PlsC ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0114 and b0115 and b0116 ) PROTEIN_ASSOCIATION: ( AceEec and AceFec and LpdA ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1638 PROTEIN_ASSOCIATION: PdxHec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0052 and b2564 ) PROTEIN_ASSOCIATION: PdxAJ SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1386 PROTEIN_ASSOCIATION: TynA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.4.3.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.8.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2320 PROTEIN_ASSOCIATION: PdxB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3916 or b1723 ) PROTEIN_ASSOCIATION: ( PfkA ) or ( PfkB ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1723 or b2168 or ( b3132 and b3137 ) ) PROTEIN_ASSOCIATION: ( PfkB ) or ( FruK ) or ( AgaZ ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.11 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3951 and b3952 ) or b3114 or ( b0902 and b0903 ) ) PROTEIN_ASSOCIATION: ( PflC ) or ( TdcE ) or ( PflA ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3176 PROTEIN_ASSOCIATION: MrsA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.4.2.10 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2913 PROTEIN_ASSOCIATION: SerA SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.95 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4025 PROTEIN_ASSOCIATION: Pgi SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2926 PROTEIN_ASSOCIATION: Pgk SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.2.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 3.1.1.31 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3385 PROTEIN_ASSOCIATION: Gph SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.1.3.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4395 or b0755 or b3612 ) PROTEIN_ASSOCIATION: ( GpmB ) or ( GpmA ) or ( YibO ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0688 or b2690 ) PROTEIN_ASSOCIATION: ( Pgmec ) or ( YqaB ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0418 or b1278 ) PROTEIN_ASSOCIATION: ( PgpAec ) or ( PgpBec ) SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 3.1.3.27 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1912 PROTEIN_ASSOCIATION: PgsA SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.7.8.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4054 or b3770 or b0928 ) PROTEIN_ASSOCIATION: ( TyrB ) or ( IlvE ) or ( AspC ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.6.1.58 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0112 or b0576 ) PROTEIN_ASSOCIATION: ( AroP ) or ( PheP ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3726 and b3725 and b3727 and b3728 ) PROTEIN_ASSOCIATION: ( PstA and PstB and PstC and PstD ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3493 or b2987 ) PROTEIN_ASSOCIATION: ( PitA ) or ( PitBec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3821 PROTEIN_ASSOCIATION: PldA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3821 PROTEIN_ASSOCIATION: PldA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3821 PROTEIN_ASSOCIATION: PldA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2048 PROTEIN_ASSOCIATION: CpsG SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2103 PROTEIN_ASSOCIATION: ThiDec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.4.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3974 PROTEIN_ASSOCIATION: CoaA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.33 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3258 PROTEIN_ASSOCIATION: PanF SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0871 PROTEIN_ASSOCIATION: PoxB SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.2.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4226 PROTEIN_ASSOCIATION: Ppa SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 3.6.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3115 PROTEIN_ASSOCIATION: TdcD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0369 PROTEIN_ASSOCIATION: HemBec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.1.24 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3956 PROTEIN_ASSOCIATION: Ppc SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.1.31 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.36 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3403 PROTEIN_ASSOCIATION: Pck SUBSYSTEM: S_Anaplerotic_reactions PROTEIN_CLASS: 4.1.1.49 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2920 PROTEIN_ASSOCIATION: YgfH SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4383 or b3380 ) PROTEIN_ASSOCIATION: ( DeoB ) or ( YhfW ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4383 PROTEIN_ASSOCIATION: DeoB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.4.2.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.3.2.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2600 PROTEIN_ASSOCIATION: TyrAec SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.3.1.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2599 PROTEIN_ASSOCIATION: PheA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.51 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3850 PROTEIN_ASSOCIATION: HemG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.3.3.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2538 and b2539 and b2540 and b2542 ) PROTEIN_ASSOCIATION: HcaCDEF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2536 PROTEIN_ASSOCIATION: HcaT SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1702 PROTEIN_ASSOCIATION: Ppsa SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.9.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4005 PROTEIN_ASSOCIATION: PurDec SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.4.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2499 PROTEIN_ASSOCIATION: PurM SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1262 PROTEIN_ASSOCIATION: TrpCec SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 5.3.1.24 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2026 PROTEIN_ASSOCIATION: HisI SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.5.4.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2476 PROTEIN_ASSOCIATION: PurC SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.2.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2026 PROTEIN_ASSOCIATION: HisI SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 3.6.1.31 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2557 PROTEIN_ASSOCIATION: PurL SUBSYSTEM: S_Purine_and_Pyrimidine_Biosynthesis PROTEIN_CLASS: 6.3.5.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2024 PROTEIN_ASSOCIATION: HisA SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 5.3.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1014 PROTEIN_ASSOCIATION: PutAec SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.5.99.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2677 and b2678 and b2679 ) PROTEIN_ASSOCIATION: ( ProVec and ProW and ProX ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4111 PROTEIN_ASSOCIATION: ProPec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1015 PROTEIN_ASSOCIATION: PutPec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1207 PROTEIN_ASSOCIATION: PrsA SUBSYSTEM: S_Histidine_Metabolism PROTEIN_CLASS: 2.7.6.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0908 PROTEIN_ASSOCIATION: AroA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.5.1.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4160 PROTEIN_ASSOCIATION: Psd SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 4.1.1.65 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0907 PROTEIN_ASSOCIATION: SerC SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 2.6.1.52 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4388 PROTEIN_ASSOCIATION: SerB SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 3.1.3.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2585 PROTEIN_ASSOCIATION: PssA SUBSYSTEM: S_Membrane_Lipid_Metabolism PROTEIN_CLASS: 2.7.8.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2297 PROTEIN_ASSOCIATION: Pta SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2297 or b2458 ) PROTEIN_ASSOCIATION: ( Pta ) or ( EutD ) SUBSYSTEM: S_Pyruvate_Metabolism PROTEIN_CLASS: 2.3.1.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3634 PROTEIN_ASSOCIATION: CoaD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.7.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0692 PROTEIN_ASSOCIATION: PotEec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.29 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b1126 and b1125 and b1124 and b1123 ) or ( b0854 and b0855 and b0856 and b0857 ) or ( b1440 and b1441 and b1442 and b1443 ) ) PROTEIN_ASSOCIATION: ( PotA and PotB and PotC and PotDec ) or ( PotF and PotG and PotH and PotI ) or ( YdcS and YdcT and YdcU and YdcV ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0692 PROTEIN_ASSOCIATION: PotEec SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2407 or b4384 ) PROTEIN_ASSOCIATION: ( XapA ) or ( DeoD ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1638 PROTEIN_ASSOCIATION: PdxHec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 1.4.3.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2418 PROTEIN_ASSOCIATION: PdxK SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2418 or b1636 ) PROTEIN_ASSOCIATION: ( PdxK ) or ( PdxYec ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2418 PROTEIN_ASSOCIATION: PdxK SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.35 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1854 or b1676 ) PROTEIN_ASSOCIATION: ( Pyka ) or ( Pykf ) SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 2.7.1.40 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3831 PROTEIN_ASSOCIATION: Udp SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0750 PROTEIN_ASSOCIATION: NadA SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0025 PROTEIN_ASSOCIATION: RibFec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1662 PROTEIN_ASSOCIATION: RibCec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0415 PROTEIN_ASSOCIATION: RibH SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3752 PROTEIN_ASSOCIATION: RbsK SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0063 PROTEIN_ASSOCIATION: AraB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0061 or b3583 or b4198 ) PROTEIN_ASSOCIATION: ( AraD ) or ( SgbE ) or ( SgaE ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.3.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2687 PROTEIN_ASSOCIATION: LuxS SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b4231 and b4227 and b4228 and b4229 and b4230 ) or ( b3749 and b3751 and b3750 and b3748 ) ) PROTEIN_ASSOCIATION: ( YjfF and YtfQ and YtfR and YtfS and YtfT ) or ( RbsA and RbsB and RbsC and RbsDec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3903 PROTEIN_ASSOCIATION: RhaA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3904 PROTEIN_ASSOCIATION: RhaB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3907 PROTEIN_ASSOCIATION: RhaT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3902 PROTEIN_ASSOCIATION: RhaD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2234 and b2235 ) PROTEIN_ASSOCIATION: NrdA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2234 and b2235 ) PROTEIN_ASSOCIATION: NrdA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2234 and b2235 ) or ( b2675 and b2676 ) ) PROTEIN_ASSOCIATION: ( NrdA ) or ( NrdE ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2234 and b2235 ) PROTEIN_ASSOCIATION: NrdA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4238 PROTEIN_ASSOCIATION: NrdD SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4238 PROTEIN_ASSOCIATION: NrdD SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4238 PROTEIN_ASSOCIATION: NrdD SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4238 PROTEIN_ASSOCIATION: NrdD SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 1.17.4.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3386 or b4301 ) PROTEIN_ASSOCIATION: ( Rpeec ) or ( SgcE ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 5.1.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2914 or b4090 ) PROTEIN_ASSOCIATION: ( RpiA ) or ( RpiB ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 5.3.1.6 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0638 PROTEIN_ASSOCIATION: PhpB SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0222 PROTEIN_ASSOCIATION: GmhA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1748 PROTEIN_ASSOCIATION: AstC SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.6.1.69 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2751 and b2752 ) PROTEIN_ASSOCIATION: CysD SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2705 PROTEIN_ASSOCIATION: SrlD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.140 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2415 and b2416 and b2702 and b2704 and b2703 ) PROTEIN_ASSOCIATION: ( PtsH and PtsI and SrlA and SrlB and SrlE ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2472 PROTEIN_ASSOCIATION: DapE SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 3.5.1.18 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.6.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1764 PROTEIN_ASSOCIATION: SelD SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 2.7.9.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0586 PROTEIN_ASSOCIATION: EntF SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3607 PROTEIN_ASSOCIATION: CysE SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 2.3.1.30 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2366 PROTEIN_ASSOCIATION: DsdA SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1814 or b2797 or b3708 or ( b3111 and b3112 ) ) PROTEIN_ASSOCIATION: ( SdaAec ) or ( SdaB ) or ( TnaA ) or ( TdcG ) SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 4.3.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2796 or b3116 ) PROTEIN_ASSOCIATION: ( SdaC ) or ( TdcC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3089 PROTEIN_ASSOCIATION: SstT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1744 PROTEIN_ASSOCIATION: AstE SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1746 PROTEIN_ASSOCIATION: AstD SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2264 PROTEIN_ASSOCIATION: MenD SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3368 PROTEIN_ASSOCIATION: CysG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3368 PROTEIN_ASSOCIATION: CysG SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3281 or b1692 ) PROTEIN_ASSOCIATION: ( AroEec ) or ( YdiB ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 1.1.1.25 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3390 or b0388 ) PROTEIN_ASSOCIATION: ( AroK ) or ( AroL ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.7.1.71 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3939 PROTEIN_ASSOCIATION: MetB SUBSYSTEM: S_Methionine_Metabolism PROTEIN_CLASS: 4.2.99.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1745 PROTEIN_ASSOCIATION: AstB SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1584 PROTEIN_ASSOCIATION: SpeG SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.57 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1584 PROTEIN_ASSOCIATION: SpeG SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.3.1.57 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b1126 and b1125 and b1124 and b1123 ) or ( b1440 and b1441 and b1442 and b1443 ) ) PROTEIN_ASSOCIATION: ( PotA and PotB and PotC and PotDec ) or ( YdcS and YdcT and YdcU and YdcV ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0121 PROTEIN_ASSOCIATION: SpeE SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 2.5.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3908 or b1656 or b1646 ) PROTEIN_ASSOCIATION: ( SodA ) or ( SodB ) or ( SodC ) SUBSYSTEM: S_Unassigned PROTEIN_CLASS: 1.15.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2661 PROTEIN_ASSOCIATION: GabD SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: 1.2.1.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2260 PROTEIN_ASSOCIATION: MenE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 6.2.1.26 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2261 PROTEIN_ASSOCIATION: MenC SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3579 PROTEIN_ASSOCIATION: YiaO SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3528 PROTEIN_ASSOCIATION: DctA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4138 or b4123 ) PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0621 PROTEIN_ASSOCIATION: DcuC SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0721 and b0722 and b0723 and b0724 ) PROTEIN_ASSOCIATION: Sdh SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 1.3.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0721 and b0722 and b0723 and b0724 ) PROTEIN_ASSOCIATION: Sdh SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4138 or b4123 or b0621 ) PROTEIN_ASSOCIATION: ( DcuA ) or ( DcuB ) or ( DcuC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0728 and b0729 ) PROTEIN_ASSOCIATION: SucC SUBSYSTEM: S_Citric_Acid_Cycle PROTEIN_CLASS: 6.2.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2417 and b2415 and b2416 and b2429 ) PROTEIN_ASSOCIATION: ( Crr and PtsH and PtsI and ScrA ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2763 and b2764 ) PROTEIN_ASSOCIATION: CysIJ SUBSYSTEM: S_Cysteine_Metabolism PROTEIN_CLASS: 1.8.2.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2422 and b2424 and b2423 and b2413 and b3917 ) or ( b2422 and b2425 and b2424 and b2423 ) ) PROTEIN_ASSOCIATION: ( CysA and CysU and CysW and CysZ and Sbp ) or ( CysA and CysP and CysU and CysW ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1521 PROTEIN_ASSOCIATION: UxaB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.1.1.58 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0008 or b2464 ) PROTEIN_ASSOCIATION: ( TalB ) or ( TalA ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3061 and b3062 ) PROTEIN_ASSOCIATION: TtdAB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.2.1.32 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3063 PROTEIN_ASSOCIATION: YgjE SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0368 PROTEIN_ASSOCIATION: TauD SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 1.14.11.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0365 and b0366 and b0367 ) PROTEIN_ASSOCIATION: ( TauA and TauB and TauC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3790 PROTEIN_ASSOCIATION: WecD SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3791 PROTEIN_ASSOCIATION: WecE SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.6.1.33 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2038 PROTEIN_ASSOCIATION: RfbC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.3.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2040 PROTEIN_ASSOCIATION: RfbD SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.133 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2041 or b3788 ) PROTEIN_ASSOCIATION: ( RfbB ) or ( RffG ) SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 4.2.1.46 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0915 PROTEIN_ASSOCIATION: LpxK SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.1.130 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b3132 and b3137 ) or ( b2095 and b2096 ) ) PROTEIN_ASSOCIATION: ( AgaZ ) or ( GatZ ) SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 4.1.2.40 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1602 and b1603 ) PROTEIN_ASSOCIATION: Pnt SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.6.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0166 PROTEIN_ASSOCIATION: DapD SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 2.3.1.117 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0068 and b0067 and b0066 ) PROTEIN_ASSOCIATION: ( SfuA and SfuB and SfuC ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0870 or b2551 ) PROTEIN_ASSOCIATION: ( LtaA ) or ( GlyA ) SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.1.2.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3616 PROTEIN_ASSOCIATION: Tdh SUBSYSTEM: S_Glycine_and_Serine_Metabolism PROTEIN_CLASS: 1.1.1.103 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3117 or b1814 or b2797 or b3772 ) PROTEIN_ASSOCIATION: ( TdcB ) or ( SdaAec ) or ( SdaB ) or ( IlvA ) SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0004 PROTEIN_ASSOCIATION: ThrC SUBSYSTEM: S_Threonine_and_Lysine_Metabolism PROTEIN_CLASS: 4.2.3.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 ) PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3116 PROTEIN_ASSOCIATION: TdcC SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3089 PROTEIN_ASSOCIATION: SstT SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2530 and b3992 and ( b3990 and b3991 ) and b0423 and b4407 ) PROTEIN_ASSOCIATION: ( IscS and ThiFec and ThiGH and ThiI and ThiS ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2935 or b2465 ) PROTEIN_ASSOCIATION: ( TktA ) or ( TktB ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2935 or b2465 ) PROTEIN_ASSOCIATION: ( TktA ) or ( TktB ) SUBSYSTEM: S_Pentose_Phosphate_Pathway PROTEIN_CLASS: 2.2.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0894 and b0895 and b0896 ) PROTEIN_ASSOCIATION: DmsABC SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0997 and b0996 ) or ( b1873 and b1872 ) ) PROTEIN_ASSOCIATION: ( TorA and TorC ) or ( TorY and TorZ ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0894 and b0895 and b0896 ) PROTEIN_ASSOCIATION: DmsABC SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b0997 and b0996 ) or ( b1873 and b1872 ) ) PROTEIN_ASSOCIATION: ( TorA and TorC ) or ( TorY and TorZ ) SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1238 PROTEIN_ASSOCIATION: Tdk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.21 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4382 PROTEIN_ASSOCIATION: DeoA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.4 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2827 PROTEIN_ASSOCIATION: ThyA SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.1.1.45 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.1.89 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0417 PROTEIN_ASSOCIATION: ThiL SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.7.4.16 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3993 PROTEIN_ASSOCIATION: ThiE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.5.1.3 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3919 PROTEIN_ASSOCIATION: Tpi SUBSYSTEM: S_GlycolysisGluconeogenesis PROTEIN_CLASS: 5.3.1.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0888 PROTEIN_ASSOCIATION: TrxB SUBSYSTEM: S_Oxidative_Phosphorylation PROTEIN_CLASS: 1.8.1.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4239 PROTEIN_ASSOCIATION: TreC SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.93 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1897 PROTEIN_ASSOCIATION: OtsB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.1.3.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1896 PROTEIN_ASSOCIATION: OtsA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.4.1.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3519 PROTEIN_ASSOCIATION: TreF SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.28 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1197 PROTEIN_ASSOCIATION: TreA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 3.2.1.28 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2417 and b2415 and b2416 and b4240 ) PROTEIN_ASSOCIATION: ( Crr and PtsH and PtsI and TreB ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3708 PROTEIN_ASSOCIATION: TnaA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.1.99.1 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1260 and b1261 ) PROTEIN_ASSOCIATION: TrpA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1260 and b1261 ) PROTEIN_ASSOCIATION: TrpA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1260 and b1261 ) PROTEIN_ASSOCIATION: TrpA SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 4.2.1.20 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3709 or b0112 or b3161 ) PROTEIN_ASSOCIATION: ( TnaB ) or ( AroP ) or ( Mtr ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3125 or b0509 ) PROTEIN_ASSOCIATION: ( GarR ) or ( GlxR ) SUBSYSTEM: S_Glyoxylate_Metabolism PROTEIN_CLASS: 1.1.1.60 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( ( b2422 and b2424 and b2423 and b3917 ) or ( b2422 and b2425 and b2424 and b2423 ) ) PROTEIN_ASSOCIATION: ( CysA and CysU and CysW and Sbp ) or ( CysA and CysP and CysU and CysW ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2344 PROTEIN_ASSOCIATION: FadL SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b4054 or b0928 ) PROTEIN_ASSOCIATION: ( TyrB ) or ( AspC ) SUBSYSTEM: S_Tyrosine__Tryptophan__and_Phenylalanine_Metabolism PROTEIN_CLASS: 2.6.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b1907 or b0576 or b0112 ) PROTEIN_ASSOCIATION: ( TyrP ) or ( PheP ) or ( AroP ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0179 PROTEIN_ASSOCIATION: LpxD SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0085 PROTEIN_ASSOCIATION: MurEec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.13 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3787 PROTEIN_ASSOCIATION: WecC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3786 PROTEIN_ASSOCIATION: WecB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.1.3.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0181 PROTEIN_ASSOCIATION: LpxA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.3.1.129 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3189 PROTEIN_ASSOCIATION: MurA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.5.1.7 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3730 PROTEIN_ASSOCIATION: GlmUec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 2.7.7.23 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0090 PROTEIN_ASSOCIATION: MurGec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0088 PROTEIN_ASSOCIATION: MurD SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0091 PROTEIN_ASSOCIATION: MurC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.8 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3972 PROTEIN_ASSOCIATION: MurB SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.158 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 3.6.1.27 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0174 PROTEIN_ASSOCIATION: UppS SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0759 PROTEIN_ASSOCIATION: GalE SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.1.3.2 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2036 PROTEIN_ASSOCIATION: Glf SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 5.4.99.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2028 PROTEIN_ASSOCIATION: Ugd SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 1.1.1.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0758 PROTEIN_ASSOCIATION: GalT SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.7.12 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0505 PROTEIN_ASSOCIATION: AllA SUBSYSTEM: S_Nitrogen_Metabolism PROTEIN_CLASS: 3.5.3.19 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0086 PROTEIN_ASSOCIATION: MurFec SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: 6.3.2.15 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0096 PROTEIN_ASSOCIATION: LpxC SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b0910 or b0171 ) PROTEIN_ASSOCIATION: ( Cmk ) or ( PyrHec ) SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.4.14 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Arginine_and_Proline_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3803 or b3368 ) PROTEIN_ASSOCIATION: ( HemX ) or ( CysG ) SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 2.1.1.107 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3804 PROTEIN_ASSOCIATION: HemDec SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.2.1.75 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3997 PROTEIN_ASSOCIATION: HemE SUBSYSTEM: S_Cofactor_and_Prosthetic_Group_Biosynthesis PROTEIN_CLASS: 4.1.1.37 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2498 PROTEIN_ASSOCIATION: Upp SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.9 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2497 PROTEIN_ASSOCIATION: UraA SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b1006 PROTEIN_ASSOCIATION: YcdG SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3927 PROTEIN_ASSOCIATION: GlpF SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0171 PROTEIN_ASSOCIATION: PyrHec SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2066 PROTEIN_ASSOCIATION: Udk SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.7.1.48 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b2964 or b2393 ) PROTEIN_ASSOCIATION: ( NupG ) or ( NupCec ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0480 PROTEIN_ASSOCIATION: UshA SUBSYSTEM: S_Cell_Envelope_Biosynthesis PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3770 PROTEIN_ASSOCIATION: IlvE SUBSYSTEM: S_Valine__Leucine__and_Isoleucine_Metabolism PROTEIN_CLASS: 2.6.1.42 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3454 and b3455 and b3457 and b3460 and b3456 ) PROTEIN_ASSOCIATION: ( LivF and LivG and LivH and LivJ and LivM ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0401 PROTEIN_ASSOCIATION: BrnQ SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3572 PROTEIN_ASSOCIATION: AvtA SUBSYSTEM: S_Alanine_and_Aspartate_Metabolism PROTEIN_CLASS: 2.6.1.66 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4197 PROTEIN_ASSOCIATION: SgaU SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: PROTEIN_ASSOCIATION: SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3654 PROTEIN_ASSOCIATION: YicE SUBSYSTEM: S_Putative_Transporters PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b0238 PROTEIN_ASSOCIATION: Gpt SUBSYSTEM: S_Nucleotide_Salvage_Pathway PROTEIN_CLASS: 2.4.2.22 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b2406 PROTEIN_ASSOCIATION: XapB SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3565 PROTEIN_ASSOCIATION: XylA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3565 PROTEIN_ASSOCIATION: XylA SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 5.3.1.5 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b3564 PROTEIN_ASSOCIATION: XylB SUBSYSTEM: S_Alternate_Carbon_Metabolism PROTEIN_CLASS: 2.7.1.17 $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: ( b3566 and b3567 and b3568 ) PROTEIN_ASSOCIATION: ( XylF and XylG and XylH ) SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$ GENE_ASSOCIATION: b4031 PROTEIN_ASSOCIATION: XylE SUBSYSTEM: S_Transport__Extracellular PROTEIN_CLASS: $\mathrm{LOWER\_BOUND}(\mathrm{UPPER\_BOUND}, \mathrm{OBJECTIVE\_COEFFICIENT}, \mathrm{FLUX\_VALUE}, \mathrm{REDUCED\_COST})$